Journal: Viruses
Article Title: Identification of Novel B Cell Epitopes on the Nucleocapsid Protein of Porcine Epidemic Diarrhea Virus
doi: 10.3390/v18030309
Figure Lengend Snippet: Localization analysis of the identified N-protein-specific epitopes. ( A ) Prediction of B-cell epitopes as antigenic targets using DNAstar Lasergene 11.1 software. The antigenic epitope 66 RIEQP 70 is highlighted with a yellow box, and the epitope 71 SNWHF 75 is highlighted with a blue box. ( B ) Three-dimensional structure of the PEDV N protein predicted by AlphaFold3, with residues color-coded according to pLDDT confidence scores. ( C ) line graph of per-residue pLDDT scores predicted by AlphaFold3. ( D ) Spatial localization of epitopes 66 RIEQP 70 and 71 SNWHF 75 within the PEDV N protein, visualized using PyMOL software and highlighted in red and yellow, respectively.
Article Snippet: Based on predictions using DNAstar Lasergene 11.1 software ( A), the PEDV N protein epitope 71 SNWHF 75 is predominantly located within a regular structure comprising β-sheets.
Techniques: Software, Residue